Glucosamine Sulphate a Natural Alternative to Aspirin

When you have strained a muscle or you have a joint pain, what do you do first? Will be taking an aspirin?

There is increasing evidence to suggest that common anti-inflammatory drugs like aspirin, used in the treatment of sports injuries and arthritis, may mask the healing process rather than promote them. The glucosamine sulphate is a precursor of a natural substance, glucosamine, the organism can be ingested in supplement form. It is an amino acid produced from glutamine and sugar needed to produce vital molecules in cells and tissue connection.

When a tissue is injured, the body goes into crisis. To heal we need to produce glucosamine daily for the formation of new connective tissue molecules. However, as we age, production of glucosamine slows down, causing the elderly who suffer from joint deterioration not heal so quickly. At present, there is discussion about which forms of glucosamine is better, sulphate, hydrochloride (HCI) Or n-acetyl-glucosamine. In fact, all forms are backed by studies that validate its effectiveness and its clinical application.

Joint Repair
• The glucosamine sulphate has important functions in the formation of nails, tendons, skin, eyes, synovial fluid, bone, ligaments and mucous secretions of the digestive, respiratory and urinanio.
• The main physiological function glucosamine sulphate in joints is to stimulate production of cartilage as well as promote the incorporation of sulfur into cartilage.
• The glucosamine sulphate is responsible for stimulating the production of substances needed for proper joint function.
• The Glucosamine is also responsible for stimulating joint repair.

Osteoarthritis

• The Osteoarthritis, also known as degenerative joint disease, is the most common form of arthritis.
• During the past 10 years, several studies have confirmed that glucosamine sulphate is extremely effective in reducing symptoms of osteoarthritis.
• Standard supplementation of glucosamine sulfate is 1000-2000 mg per day.

I am a pharmacist having a masters degree in pharmacy. I always take a forward step in making people aware about certain drugs whose use is on the rise like as Glucosamine

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Gulcosamine Sulphate the Best Cure for OsteoArthritis

The human body produces glucosamine which makes it a natural substance. Physiological functions of joints are to stimulate the production of substances called glycosaminoglycans (structural components of cartilage ) as well as promote the incorporation of sulphur (element we get from food) in the cartilage.
Given this fact, glucosamine sulphate may be the best form of glucosamine. There are no foods rich in glucosamine, commercially available sources of glucosamine are extracted from the shell or shell of shrimp, lobsters and crabs.
The ability to produce enough glucosamine declines as age progresses. The result is that the cartilage of the joint loses its ability to act as shock absorbers. The weight bearing joints of the body, such as knees and hips and the hands, are most affected. In the affected joints is a greater amount of cartilage destruction followed by hardening and formation of bumps on the margins of the joints, resulting in pain, deformity and limited joint movement.
The glucosamine is available as glucosamine sulphate, hydrochloride and N-acetyl derivative. It is preferred and therefore, to which reference will be made in the rest of the article. Detailed studies in humans on the absorption, distribution and elimination of oral glucosamine sulphate, shows a 98% absorption. Once absorbed, it travels primarily to joint tissues, where it is incorporated into the matrix of connective tissue, cartilage, ligaments and tendons.
The main use of this drug is the treatment of osteoarthritis or degenerative joint disease, most common form of arthritis. Glucosamine is a natural, safe, effective alternative to aspirin and other NSAIDs. Clinical & Experimental Research indicate that the current drugs used to treat osteoarthritis may produce short-term benefits on the symptoms but actually accelerating the process of joint destruction. A side effect is often not mentioned of aspirin and other nonsteroidal anti-inflammatory drugs (like indomethacin) is the inhibition of cartilage repair and accelerated the destruction. Several double-blind scientific studies have shown that it produces better results than NSAIDs in relieving pain and inflammation of osteoarthritis, despite the fact that glucosamine shows little direct anti-inflammatory and analgesic effects shows no Direct (remove the pain.) While non-steroidal anti-inflammatory drugs relieves symptoms and may actually promote the disease process, glucosamine sulphate seems to be the cause of osteoarthritis.
The beneficial results of glucosamine are more obvious in the long run, since it is not an anti-inflammatory or analgesic by itself, so it takes more time to appreciate its benefits compared with those of non-steroidal anti-inflammatory drugs. For example, a study comparing glucosamine sulphate to ibuprofen (Advil active substance, to name one) on joint pain. It decreased more in the first two weeks in the ibuprofen group. However, for the fourth week the glucosamine sulphate group did better benefits because it diminishes the pain in a significantly greater extent than the anti-inflammatory, regeneration was articulate, a situation that it will continue for several months after the end treatment.
To date, glucosamine sulphate is well tolerated and no allergic reactions have been reported. Studies in athletes with osteoarthritis have shown excellent results on the painful inflammation and the benefits of glucosamine remain weeks after discontinued use. If you want to take glucosamine sulphate consult your health care professional familiar with the use of nutritional supplements, if you have diabetes should take extra precautions.

I am Pharmacist by profession and have a masters degree in pharmacology and have interest in making people aware about the latest drugs which have great role to play like Glucosamine

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What is Glucosamine and Chondroitin Sulphate?

Glucosamine and Chondroitin are nutritional supplements and as such are not subject to the same strict regulations required for prescription drugs and prescription. Therefore, if you decide to take any supplement, you do so on your own. Be sure to consult your doctor before trying these supplements. Make sure that the cause of your pain is osteoarthritis (OA). Do not stop or reduce the dosage of prescription drugs currently taken without consulting your doctor.

What is Glucosamine and Chondroitin Sulphateate?

* Glucosamine and chondroitin sulphate are substances that occur naturally in the body.

Glucosamine:

* Glucosamine is a aminosacárido which plays an important role in cartilage formation and repair.
* Glucosamine is extracted from crab, lobster or shrimp shells.

Chondroitin Sulphate:

* Chondroitin sulphate is part of a large protein molecule (proteoglycan) that gives cartilage elasticity.
* Chondroitin sulphate is extracted, in most cases, the cartilage of the trachea of cattle, but in Japan also is extracted from shark cartilage.

Why do we use these supplements?

* These supplements have been used to treat osteoarthritis (OA) in horses and dogs for many years.
* In Europe, glucosamine and chondroitin sulphate is used to treat OA in humans since the 1980's.
* It is important to remember that these supplements have not been studied as a treatment for other forms of arthritis or related diseases, such as rheumatoid arthritis (RA) and gout, or treat other causes of pain, such as stress fractures.

What Do these supplements do?

* In studies conducted mainly in Europe, some people with mild to moderate OA who took glucosamine and chondroitin sulphate showed some pain relief and improved joint function. Reports indicate that these supplements relieve pain similarly to NSAIDs such as aspirin, ibuprofen and naproxen sodium.
* Limited studies have been conducted double-blind controlled long-term to assess the benefits or safety.

What characteristics should the supplement posses?

* Glucosamine comes in several forms, the most common are glucosamine sulphate and glucosamine hydrochloride. It was found that both forms are equally effective, although most studies were conducted in the form of sulfate.
* The shark cartilage products containing chondroitin sulfate, but the amount and quality of chondroitin sulfate is not consistent.
* Since dietary supplements are not regulated, the quality and content can vary widely.

Some tips for picking quality products are:

* Choose a product manufactured by a large company who can be responsible and serious
* Read labels carefully to make sure that the ingredient list makes sense
* Ask for recommendations from your doctor or pharmacist

How doo we you should take this supplement?

* If you take these supplements, experts recommend taking the amount used in most clinical trials:
o Glucosamine: 1,500 mg (milligrams) per day
o Chondroitin: 1,200 mg per day
* If this dose relieves symptoms can decrease the amount gradually after a few months.
* Generally we recommend taking glucosamine and chondroitin sulphate together, but do not know for sure if the combination takes a better effect than the individual use of each substance.
* You should plan the use of supplements along with current medications for 6 to 8 weeks. If the pain decreases, then you can ask your doctor whether you should reduce or stop the other drugs for a while to see if there are any changes in the levels of pain and stiffness.
* If after four to six months do not notice any change in symptoms, probably the supplements did not provide any relief. Some people may experience partial relief using supplements, but may have to continue taking medication for a complete relief.

"These supplements have side effects?

* Both glucosamine and chondroitin sulphate may have the following effects:
o Increased intestinal gas
o Softer stools
* Further studies should be performed to confirm the safety and efficacy of supplements. Be sure to consult your doctor if you notice any new or unusual symptoms when taking these supplements.

Precautions

* Children, pregnant women and women who may become pregnant should not take these supplements. These substances have not been studied enough to determine the possible effects on a developing fetus or a child.

People showing the conditions set forth below should take precautions with these supplements:

Glucosamine:

* Diabetes, because glucosamine is a aminosacárido, people with diabetes should control their blood sugar levels more often when taking these supplements.
* Allergy to seafood, if you are allergic to shellfish, consult your doctor before taking glucosamine. In most cases, allergies are caused by proteins found in shellfish, not by chitin, a carbohydrate from which glucosamine is extracted.

Chondroitin Sulphate:

* This supplement may contain a similar structure to heparin, an anticoagulant drug, and the combination could increase the risk of bleeding.
* People taking anticoagulant medicines in combination with chondroitin sulphate should be monitored prothrombin time and coagulation more frequently.

Glucosamine and Chondroitin are nutritional supplements and as such are not subject to the same strict regulations required for prescription drugs and prescription. Therefore, if you decide to take any supplement, you do so on your own. Be sure to consult your doctor before trying these supplements. Make sure that the cause of your pain is osteoarthritis (OA). Do not stop or reduce the dosage of prescription drugs currently taken without consulting your doctor.

What is Glucosamine and Chondroitin Sulphateate?

* Glucosamine and chondroitin sulphate are substances that occur naturally in the body.

Glucosamine:

* Glucosamine is a aminosacárido which plays an important role in cartilage formation and repair.
* Glucosamine is extracted from crab, lobster or shrimp shells.

Chondroitin Sulphate:

* Chondroitin sulphate is part of a large protein molecule (proteoglycan) that gives cartilage elasticity.
* Chondroitin sulphate is extracted, in most cases, the cartilage of the trachea of cattle, but in Japan also is extracted from shark cartilage.

Why do we use these supplements?

* These supplements have been used to treat osteoarthritis (OA) in horses and dogs for many years.
* In Europe, glucosamine and chondroitin sulphate is used to treat OA in humans since the 1980's.
* It is important to remember that these supplements have not been studied as a treatment for other forms of arthritis or related diseases, such as rheumatoid arthritis (RA) and gout, or treat other causes of pain, such as stress fractures.

What Do these supplements do?

* In studies conducted mainly in Europe, some people with mild to moderate OA who took glucosamine and chondroitin sulphate showed some pain relief and improved joint function. Reports indicate that these supplements relieve pain similarly to NSAIDs such as aspirin, ibuprofen and naproxen sodium.
* Limited studies have been conducted double-blind controlled long-term to assess the benefits or safety.

What characteristics should the supplement posses?

* Glucosamine comes in several forms, the most common are glucosamine sulphate and glucosamine hydrochloride. It was found that both forms are equally effective, although most studies were conducted in the form of sulfate.
* The shark cartilage products containing chondroitin sulfate, but the amount and quality of chondroitin sulfate is not consistent.
* Since dietary supplements are not regulated, the quality and content can vary widely.

Some tips for picking quality products are:

* Choose a product manufactured by a large company who can be responsible and serious
* Read labels carefully to make sure that the ingredient list makes sense
* Ask for recommendations from your doctor or pharmacist

How doo we you should take this supplement?

* If you take these supplements, experts recommend taking the amount used in most clinical trials:
o Glucosamine: 1,500 mg (milligrams) per day
o Chondroitin: 1,200 mg per day
* If this dose relieves symptoms can decrease the amount gradually after a few months.
* Generally we recommend taking glucosamine and chondroitin sulphate together, but do not know for sure if the combination takes a better effect than the individual use of each substance.
* You should plan the use of supplements along with current medications for 6 to 8 weeks. If the pain decreases, then you can ask your doctor whether you should reduce or stop the other drugs for a while to see if there are any changes in the levels of pain and stiffness.
* If after four to six months do not notice any change in symptoms, probably the supplements did not provide any relief. Some people may experience partial relief using supplements, but may have to continue taking medication for a complete relief.

"These supplements have side effects?

* Both glucosamine and chondroitin sulphate may have the following effects:
o Increased intestinal gas
o Softer stools
* Further studies should be performed to confirm the safety and efficacy of supplements. Be sure to consult your doctor if you notice any new or unusual symptoms when taking these supplements.

Precautions

* Children, pregnant women and women who may become pregnant should not take these supplements. These substances have not been studied enough to determine the possible effects on a developing fetus or a child.

People showing the conditions set forth below should take precautions with these supplements:

Glucosamine:

* Diabetes, because glucosamine is a aminosacárido, people with diabetes should control their blood sugar levels more often when taking these supplements.
* Allergy to seafood, if you are allergic to shellfish, consult your doctor before taking glucosamine. In most cases, allergies are caused by proteins found in shellfish, not by chitin, a carbohydrate from which glucosamine is extracted.

Chondroitin Sulphate:

* This supplement may contain a similar structure to heparin, an anticoagulant drug, and the combination could increase the risk of bleeding.
* People taking anticoagulant medicines in combination with chondroitin sulphate should be monitored prothrombin time and coagulation more frequently.

View the original article here